GE AKTA avant User Manual page 513

Parameter
Pressure con-
trol min flow
rate
Recommended pressure control
parameters
The following table contains the recommended values for P and I parameters for different
media types.
Column/Media
Default
Small soft media
columns
Large soft
columns
Small rigid
columns
1
2
Back pressure
Using narrow tubing between components will improve resolution but will lead to in-
creased back pressure in the system. Narrow tubing after the column will increase the
pressure in the column at a given flow rate. Make sure that the pressure sensor limits
in the system are set so that the maximum pressure for the column used is not exceeded.
ÄKTA avant User Manual 29035184 AE
Description
If the flow rate is reduced below the value set in Pressure control
min flow rate, the method is paused and the system is set to state
ALARMS AND ERRORS.
Pressure control min flow rate can be set either as volumetric or
as linear flow. A column type must be selected before using linear
flow.
Recom-
mended P
factor
8
8
1
media 8
2
media 8
20
Soft media is defined as all GE separation media, except silica and MonoBeads.
Rigid media is defined as GE separation media that is based on silica and MonoBeads.
9 Reference information
Recommend- Additional information
ed I factor
40 N/A
40 N/A
300 - 600 A higher I value than the de-
fault value is needed to speed
up pressure ramp-up times.
15 A lower I value than the default
value is needed to avoid large
40
fluctuations in pressure or flow
rate. As an alternative, try in-
creasing P.
9.14 Pressure control
513