Epson AcuLaser C4100 Reference Manual page 227

7. Turn the toner cartridge knobs to the locked position.
Note:
Hold the knobs with both hands and turn them until they click.
Caution:
c
Be sure to turn the knob all the way to the locked position.
Otherwise, you may have toner problems or leakage.
8. Remove the protective tape, pulling straight up from the toner
cartridge.
Replacing Consumable Products
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