Unicorn Method For System Cip/Sanitization/Rinsing; 0.00 Filter Inline - GE AKTAprocess Operating Instructions Manual

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8.5 UNICORN method for system CIP/Sanitization/Rinsing

8.5

UNICORN method for system CIP/Sanitization/Rinsing

Introduction
This section provides an example of a complete method that may be used for system
cleaning.
Main method
The method outlined here is an example designed for a 2-pump, 10 mm inner diameter
system (max flow 600 l/h). CIP solution in this example is 1 M sodium hydroxide.
Note:
(Main)
0.00 Base Time
0.00 Air_Alarm Disabled Disabled
0.00 Gradient 0.0 {%B} 0.00 {base}
0.00 InletCIP InletCIP1
0.00 InletA InletA1
0.00 AirTrap Inline

0.00 Filter Inline

0.00 Column UpFlow
0.00 Outlet Outlet1
0.00 Flow 450 {l/hour}
0.00 Block Fill_CIP_inlet
(Fill_CIP_inlet)
0.00 Base SameAsMain
0.00 InletCIP InletCIP1
1.00 End_Block
0.00 Block Fill_all_A_inlets
(Fill_all_A_inlets)
0.00 Base SameAsMain
0.00 InletA InletA1
0.50 InletA InletA2
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The CIP method below does not include the optional sample pump. If a sample
pump is part of the system, it should always be cleaned first. The UNICORN
method must be changed accordingly, so that it starts with the sample pump
inlets.
ÄKTAprocess Operating Instructions 29-0252-49 AA