Waters Xevo G2-XS QTof Manuals

Manuals and User Guides for Waters Xevo G2-XS QTof. We have 3 Waters Xevo G2-XS QTof manuals available for free PDF download: Overview And Maintenance Manual, Quick Start Manual

Waters Xevo G2-XS QTof Overview And Maintenance Manual (283 pages)

Brand: Waters | Category: Laboratory Equipment | Size: 6.94 MB

General Information
2
Trademarks
2
Customer Comments
3
Contacting Waters
3
Legal Manufacturer
4
Safety Considerations
4
Considerations Specific to the Device
4
Electrical Power Safety Notice
7
Safety Hazard Symbol Notice
7
Equipment Misuse Notice
7
Safety Advisories
7
Operating the Device
8
Applicable Symbols
8
Audience and Purpose
9
Intended Use of the Xevo G2-XS Qtof
9
Quality Control
9
Equipment Misuse Notice
10
EMC Considerations
10
FCC Radiation Emissions Notice
10
ISM Classification: ISM Group 1 Class a
10
EMC Emissions
11
Table of Contents
12
Waters Xevo G2-XS Qtof Overview
20
Waters Xevo G2-XS Qtof
20
Intellistart Technology
20
ACQUITY UPLC/MS Xevo G2-XS Qtof Systems
21
Software and Data System
25
Lockspray Source and Ionization Modes
26
Electrospray Ionization (ESI)
26
Atmospheric Pressure Chemical Ionization (APCI)
27
Combined Electrospray/Atmospheric Pressure Chemical Ionization (Esci)
27
Atmospheric Solids Analysis Probe (ASAP)
28
Nanolockspray Source and Ionization Modes
28
Combined APPI/APCI Source
29
Atmospheric Pressure Gas Chromatography (APGC)
30
Ionkey Source
30
Unispray Lockspray Source
30
Intellistart Fluidics System
31
Fluidics System Overview
31
Intellistart Fluidics System Physical Layout
31
System Operation
33
Ion Optics
33
Leak Sensors
35
Vacuum System
35
Preparing the Mass Spectrometer for Operation
36
Starting the Mass Spectrometer
36
Verifying the Instrument's State of Readiness
38
Monitoring the Mass Spectrometer Leds
38
Calibration
38
Flow Rates for the Xevo G2-XS Qtof System
38
Preparing the Fluidics System
39
Installing the Reservoir Bottles
39
Installing the Low-Volume Vials
40
Adjusting the Solvent Delivery Tube Positions
41
Purging the Pump
42
Rebooting the Mass Spectrometer
42
Leaving the Mass Spectrometer Ready for Operation
43
Emergency Shutdown
43
Configuring the Lockspray Source
44
Configuring the Lockspray II Source
44
Configuring for ESI Mode
44
Installing the ESI Probe
44
Removing the ESI Probe
48
Configuring for APCI Mode
48
Installing the Ionsabre II Probe
49
Removing the Ionsabre II Probe
51
Configuring for Esci Mode
51
Optimizing the ESI Probe for Esci Operation
52
Configuring the Nanolockspray Source
53
Overview of the Nanolockspray Source
53
Sample Sprayer
55
Lockspray Sprayer
55
Nanoflow Gas Supply
55
Purge Gas
55
Sprayer Platform Adjuster Assembly
55
Selecting and Configuring the Nanolockspray Source
56
Deploying the Sprayer Platform Adjuster Assembly
56
Moving the Sprayer Platform out of the Source
56
Moving the Sprayer Platform into the Source
57
Adjusting the Sprayer Tip Position
57
Setting up the Camera
57
Optional Glass Capillary Sprayer
59
Plumbing the Fluidics Sample Delivery System for Nanolockspray Operation
59
Installing and Removing the Ionkey Source
66
Ionkey Source
66
Installing the Ionkey Source
66
Installing the Ionkey Source
68
Installing Ionkey Source Software
75
Installing the Camera in the Ionkey Source
76
Removing an Ionkey Source
76
Flow Rates for the Xevo G2-XS Qtof System
78
Unispray Lockspray Source
79
Installing the Unispray Source
81
Installing the Unispray Lockspray Source
81
Removing the Unispray Source
84
Removing the Unispray Lockspray Source
84
Maintenance Procedures
86
Maintenance Schedule
86
Spare Parts
88
Safety and Handling
88
Preparing the Instrument for Working on the Source
89
Using Masslynx Software to Prepare the Instrument for Operations on or Inside Its Source
90
Using UNIFI Software to Prepare the Instrument for Working on the Source
90
Removing and Refitting the Source Enclosure
90
Removing the Source Enclosure from the Instrument
91
Fitting the Source Enclosure to the Instrument
92
Installing and Removing the Corona Pin
93
Installing the Corona Pin in the Source
93
Removing the Corona Pin from the Source
95
Operating the Source Isolation Valve
96
Closing the Source Isolation Valve
97
Opening the Source Isolation Valve
98
Removing O-Rings and Seals
99
O-Ring Removal Kit
99
Cleaning the Instrument Case
100
Emptying the Nitrogen Exhaust Trap Bottle
100
Maintaining the Roughing Pump
102
Maintaining the Oil-Filled Roughing Pump
103
Gas Ballasting the Oil-Filled Roughing Pump
104
Inspecting the Roughing Pump Oil Level
105
Adding Oil to the Roughing Pump
105
Replacing the Roughing Pump's Oil and Oil Demister Elements
107
Cleaning the Source Components
113
Cleaning the Sampling Cone Assembly
113
Removing the Sampling Cone Assembly from the Source
114
Disassembling the Sampling Cone Assembly
115
Cleaning the Sample Cone and Cone Gas Nozzle
118
Assembling the Sampling Cone Assembly
119
Fitting the Sampling Cone Assembly to the Source
120
Cleaning the Ion Block Assembly
121
Removing the Ion Block Assembly from the Source Assembly
122
Disassembling the Source Ion Block Assembly
123
Cleaning the Ion Block Components
128
Assembling the Source Ion Block Assembly
129
Fitting the Ion Block Assembly to the Source Assembly
130
Cleaning the Stepwave Ion Guide Assembly
131
Handling the Stepwave Ion Guide Assembly
131
Removing the Ion Block Support from the Source Assembly
131
Removing the Stepwave Assembly from the Source Assembly
133
Disassembling the Stepwave Ion Guide Assembly
137
Cleaning the Stepwave Ion Guide Assembly
139
Assembling the Stepwave Ion Guide Assembly
142
Fitting the Stepwave Assembly to the Source Assembly
143
Fitting the Ion Block Support to the Source
145
Maintaining the ESI Probe
146
Replacing the ESI Probe Tip and Gasket
146
Replacing the ESI Probe Capillary
149
Cleaning the Ionsabre II Probe Tip
167
Replacing the Ionsabre II Probe Sample Capillary
167
Removing the Existing Capillary
167
Installing the New Capillary
170
Replacing the Lockspray Reference Probe Capillary
172
Removing the Existing Capillary
173
Installing the New Capillary
175
Replacing the Lockspray II Reference Probe
178
Removing the Existing One-Piece Reference Probe
180
Installing the New Reference Probe
184
Replacing the Nanolockspray Reference Probe Tapertip Emitter or Capillary
188
Removing the Nanolockspray Reference Probe
188
Installing the New Tapertip Emitter and Capillary
190
Replacing the Ionkey Reference-Probe Capillary
192
Removing the Ionkey Reference-Probe Capillary
192
Cleaning or Replacing the Corona Pin
197
Maintaining the Unispray Impactor Pin
198
Cleaning or Replacing the Unispray Impactor Pin
199
Removing and Installing the Unispray Impactor Pin
199
Replacing the Unispray Probe Assembly
200
Removing the Unispray Probe Assembly
200
Installing the Unispray Probe Assembly
201
Replacing the Ionsabre II Probe Heater
203
Removing the Ionsabre II Probe Heater
203
Fitting the New Ionsabre II Probe Heater
205
Replacing the Ion Block Source Heater
206
Replacing the Source Assembly Seals
209
Removing the Probe Adjuster Assembly Probe and Source Enclosure Seals
210
Fitting the New Source Enclosure and Probe Adjuster Assembly Probe Seals
212
Replacing the Mass Spectrometer's Air Filters
213
Replacing the Air Filter Inside the Front Door
213
Replacing the Air Filters on the Sides of the Instrument
215
Replacing the Intellistart Fluidics Tubing
217
Replacing Intellistart Fluidics Tubing (Standard Configuration)
217
Intellistart Fluidics System Physical Layout
217
Removing the Intellistart Fluidics Tubing
219
Plumbing the Intellistart Fluidics Lockspray System
220
Plumbing the Intellistart Fluidics Sample Delivery System
227
Plumbing the Fluidics Sample Delivery System for Nanolockspray Operation
233
Replacing the Fluidic Lines of the Ionkey Source
239
Removing a Fluid Line
240
Installing a Fluid Line
241
Cleaning the Ionkey Source and Connectors
242
A Safety Advisories
245
Warning Symbols
245
Specific Warnings
246
Notices
247
Bottles Prohibited Symbol
248
Required Protection
248
Warnings that Apply to All Waters Instruments and Devices
248
Warnings that Address the Replacement of Fuses
252
Electrical Symbols
254
Handling Symbols
255
B External Connections
256
Mass Spectrometer External Wiring and Vacuum Connections
256
Connecting the Oil-Filled Roughing Pump
258
Making the Electrical Connections to the Oil-Filled Roughing Pump
262
Connecting the Edwards Oil-Free Roughing Pump
263
Making the Electrical Connections to the Edwards Oil-Free Roughing Pump
266
Connecting to the Nitrogen Gas Supply
267
Connecting to the Collision Cell Gas Supply
268
Connecting the Nitrogen Exhaust Line
269
Connecting Liquid Waste Lines
271
Connecting the Workstation (Systems with no ACQUITY LC)
272
Connecting to the Workstation
273
Connecting the Workstation to the Power Source
273
Connecting Ethernet Cables (Systems with ACQUITY LC)
273
Input/Output Signal Connectors
274
Signal Connections
276
Connecting the Contact-Closure Cable to an ACQUITY LC
278
Connecting to the Electricity Source
280
Connecting the Camera for the Nanolockspray Source or Ionkey Source
280
Installing the Camera Driver Software
281
C Materials of Construction and Compatible Solvents
282
Preventing Contamination
282
Items Exposed to Solvent
282
Solvents Used to Prepare Mobile Phases
283

Waters Xevo G2-XS QTof Overview And Maintenance Manual (306 pages)

Brand: Waters | Category: Laboratory Equipment | Size: 5.12 MB

Copyright Notice

3
Trademarks

3
Customer Comments

4
Contacting Waters

4
Safety Considerations

5
Operating the Xevo G2-XS Qtof

10
- Applicable Symbols
  10
- Audience and Purpose
  11
- Calibrating
  11
- Quality Control
  12
- Equipment Misuse Notice
  12
EMC Considerations

13
- Canada Spectrum Management Emissions Notice
  13
- ISM Classification: ISM Group 1 Class a
  13
EC Authorized Representative

14
- Table of Contents
  15
1 Waters Xevo G2-XS Qtof Overview

23
2 Preparing the Mass Spectrometer for Operation

45
3 Configuring the Lockspray Source

55
- Configuring the Lockspray Source
  
  56
- Configuring for ESI Mode
  
  57
  - Installing the ESI Probe
    57
  - Removing the ESI Probe
    61
- Configuring for APCI Mode
  
  62
  - Installing the Ionsabre II Probe
    62
  - Removing the Ionsabre II Probe
    65
- Configuring for Esci Mode
  
  66
  - Optimizing the ESI Probe for Esci Operation
    66
4 Configuring the Nanolockspray Source

67
- Overview of the Nanolockspray Source
  
  68
  - Sample Sprayer
    69
  - Lockspray Sprayer
    69
  - Nanoflow Gas Supply
    70
  - Purge Gas
    70
  - Sprayer Platform Adjuster Assembly
    70
- Selecting and Configuring the Nanolockspray Source
  
  71
- Deploying the Sprayer Platform Adjuster Assembly
  
  72
- Adjusting the Sprayer Tip Position
  
  73
- Setting up the Camera
  
  74
- Optional Glass-Capillary Sprayer
  
  75
5 Installing and Removing the Ionkey Source

77
6 Maintenance Procedures

91
A Safety Advisories

257
- Warning Symbols
  
  258
  - Specific Warnings
    259
- Notices
  
  262
- Prohibition Symbol
  
  262
- Warnings that Apply to All Waters Instruments and Devices
  
  263
- Warnings that Address the Replacing of Fuses
  
  268
- Electrical and Handling Symbols
  
  270
  - Electrical Symbols
    270
  - Handling Symbols
    271
B External Connections

273
C Materials of Construction and Compatible Solvents

303
- Preventing Contamination
  
  303
- Items Exposed to Solvent
  
  304
- Solvents Used to Prepare Mobile Phases
  
  305

Waters Xevo G2-XS QTof Quick Start Manual (2 pages)

No flow from fluidics

Brand: Waters | Category: Laboratory Equipment | Size: 0.04 MB

Symptoms
1
Environment
1
Cause
2
FIX or WORKAROUND
2
Additional Information
2

Waters Categories

Laboratory Equipment Security Sensors Control Unit Measuring Instruments Water Pump

More Waters Manuals

Waters Xevo G2-XS QTof Manuals

Waters Xevo G2-XS QTof Overview And Maintenance Manual (283 pages)

Table of Contents

Waters Xevo G2-XS QTof Overview And Maintenance Manual (306 pages)

Table of Contents

Copyright Notice

Trademarks

Customer Comments

Contacting Waters

Safety Considerations

Operating the Xevo G2-XS Qtof

EMC Considerations

EC Authorized Representative

1 Waters Xevo G2-XS Qtof Overview

Lockspray Source and Ionization Modes

Nanolockspray Source and Ionization Modes

Combined APPI/APCI Source

Atmospheric Pressure Gas Chromotography (APGC) Source

Ionkey Source

Intellistart Fluidics System

Ion Optics

Leak Sensors

Vacuum System

2 Preparing the Mass Spectrometer for Operation

Starting the Mass Spectrometer

Preparing the Intellistart Fluidics System

Rebooting the Mass Spectrometer

Leaving the Mass Spectrometer Ready for Operation

Emergency Shutdown of the Mass Spectrometer

3 Configuring the Lockspray Source

Configuring the Lockspray Source

Configuring for ESI Mode

Configuring for APCI Mode

Configuring for Esci Mode

4 Configuring the Nanolockspray Source

Overview of the Nanolockspray Source

Selecting and Configuring the Nanolockspray Source

Deploying the Sprayer Platform Adjuster Assembly

Adjusting the Sprayer Tip Position

Setting up the Camera

Optional Glass-Capillary Sprayer

5 Installing and Removing the Ionkey Source

Installing the Ionkey Source

Installing Ionkey Source Software

Installing the Camera in the Ionkey Source

Removing the Ionkey Source

6 Maintenance Procedures

Maintenance Schedule

Spare Parts

Troubleshooting with Connections INSIGHT

Safety and Handling

Preparing the Instrument for Working on the Source

Removing and Refitting the Source Enclosure

Installing and Removing the Corona Pin

Operating the Source Isolation Valve

Removing O-Rings and Seals

Cleaning the Instrument Case

Emptying the Nitrogen Exhaust-Trap Bottle

Maintaining the Roughing Pump

Maintaining the Oerlikon Leybold Oil-Filled Roughing Pump

Cleaning the Source Components

Cleaning the Sampling Cone Assembly

Cleaning the Ion Block Assembly

Cleaning the Stepwave Ion Guide Assembly

Replacing the ESI Probe Tip and Gasket

Replacing the ESI Probe Sample Capillary

Cleaning the Ionsabre II Probe Tip

Replacing the Ionsabre II Probe Sample Capillary

Replacing the Lockspray Reference Probe Capillary

Replacing the Nanolockspray Reference-Probe Tapertip Emitter or Capillary

Replacing the Ionkey Reference-Probe Capillary

Cleaning or Replacing the Corona Pin

Replacing the Ionsabre II Probe Heater

Replacing the Ion Block Source Heater

Replacing the Lockspray Source's Assembly Seals

Replacing the Mass Spectrometer's Air Filters

Replacing the Intellistart Fluidics Tubing

Replacing Intellistart Fluidics Tubing (Standard Configuration)

Plumbing the Sample Fluidics Delivery System for Nanolockspray Operation

Replacing the Fluid Lines of the Ionkey Source