Troubleshooting The Results Of The System Leak Test - Thermo Scientific EASY-nLC 1200 Troubleshooting And Maintenance Manual

Troubleshooting the Results of the System Leak Test

Table 26. Output messages for a system leak test and actions to take when this test fails
Message
System tight.
(Sensor A <100nl/min)
Flow sensor A should be calibrated.
The 0 nL/min point is off by more than ±30 nL/min, so
the script cannot determine leaks.
Flow sensor B should be calibrated.
The 0 nL/min point is off by more than ±30 nL/min, so
the script cannot determine leaks.
Check valve S for leaks. (Flow sensor A >100 nL/min)
Check the sample loop for leaks.
Check the B solvent line (valve to flow sensor) and valve
B for leaks. (Flow sensor B ±30 nL/min)
Check from pump A to flow sensor A for leaks. (Pump A
flow loss >1000 nL/min)
Check from valve S to valve W, including valve W, for
leaks.
Check solvent lines between flow sensor A and valve S,
including the mixing Tee and flow sensor B, for leaks.
Thermo Scientific
6. Depending on the message displayed on the Output page of the Test – Leaks script, take
the appropriate action as listed in
Table 26 lists the actions required to troubleshoot the results of a system leak test.
Tip The
"Using nanoViper Fittings Quick Reference Guide"
to return the solvent lines in the flow path of the EASY-nLC 1200 instrument to
atmospheric pressure. Print this reference guide to refer to while troubleshooting leaks
coming from the nanoViper tubing connections.
Troubleshooting the Results of the System Leak Test
Table 26.
Action
No action is required; however, the system leak test does
not test for a a leak in valve B or pump B.
Rerun the system leak test. If the same message appears,
run the Flow Sensor script to calibrate flow sensor A
(see "Flow Sensors" on page
Rerun the system leak test. If the same message appears,
run the Flow Sensor script to calibrate flow sensor B
(see "Flow Sensors" on page
Go to "Checking Valve S for Leaks"
Go to "Checking the Sample Loop Connections for
Leaks" on page 184.
Go to "Locating Leaks in the Solvent Path from Valve B
to Flow Sensor B" on page
Go to "Locating Leaks in the Solvent Path from Pump A
to Flow Sensor A" on page
Go to "Locating Leaks In or Between Valve S and
Valve W" on page 188.
Go to "Locating Leaks Between the Flow Sensors and
Valve S" on page 196.
EASY-nLC 1200 Troubleshooting & Maintenance Guide
7
Troubleshooting
on page 273 describes how
52).
52).
on page 184.
184.
186.
183