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COBAS INTEGRA 400 plus analyzer
Cedex Bio HT Analyzer
Host Interface Manual
Version 1.24
Software version 3.6/5.1

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Summary of Contents for Roche COBAS INTEGRA 400 plus

  • Page 1 COBAS INTEGRA 400 plus analyzer Cedex Bio HT Analyzer Host Interface Manual Version 1.24 Software version 3.6/5.1...
  • Page 2: Publication Information

    - i_flags: Additional Flag X/C function for I400 V2.0 and I800 - i_lc55: Nov.1999 Test ID > Test No. y Revision history Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 3 Roche Diagnostics. Leave tasks that are not described in the user documentation to trained Roche Service representatives. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 4 COBAS INTEGRA 400 plus analyzer or Cedex Bio HT Analyzer. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 5 The following marks demonstrate compliance: For in vitro diagnostic use. Complies with the provisions of the applicable EU directives. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 6 RoHS compliant from Serial No. 610001. Issued by Underwriters Laboratories, Inc. (UL) for Canada and the US. ® Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 7: Table Of Contents

    About line codes Setting up the instrument for host List of line codes communication About the RS-232 serial interface Index Index Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 8 Table of contents Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 9: Intended Use For Cobas Integra 400 Plus Analyzer

    Cedex Bio HT Analyzer instrument Host computer, laboratory information host system or other computer system connected to the instrument y Product names Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 10: What Is New In Publication Version 1.24

    Approvals for the Cedex Bio HT Analyzer The approvals for the Cedex Bio HT Analyzer were rephrased. u Approvals for Cedex Bio HT Analyzer (6) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 11: What Is New In Publication Version 1.23

    Information about the Cedex Bio HT Analyzer has been added to this publication. • No other content changes have been made. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 12 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 13 Communication About communication ..................15 About host interface features ................27 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 15 Host communication handling ....Synchronization and sequence counter use..Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 16 Table of contents Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 17: Communication Concept

    If the host does not receive a response upon a request within a certain time, a timeout should be activated. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 18: Message Structure

    1<LF> (0 or 2 lines) 562<LF> <EOT><LF> In this section Block header (19) Block data (19) Block check (20) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 19: Block Header

    Related topics • Block codes (59) • Line codes (81) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 20: Block Check

    Structure of block check Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 21: Communication Control

    (block 99). Host systems will use the error handling. u Related topics • Error handling (24) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 22: Flow Control (Hardware/Software Handshake)

    We strongly recommend that you enable the block check. Otherwise you cannot be sure that all data are correctly transmitted. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 23: Check Of Block And Line Composition

    Incompletely received messages (without an <EOT> termination) will not be acknowledged by the instruments (host time-out). u Related topics • Error handling (24) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 24: Error Handling

    General error message (block 99) was received • Time-out occurred u Related topics • Synchronization and sequence counter use (26) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 25: Host Communication Handling

    About communication Host communication handling w Suggestion for host communication handling Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 26: Synchronization And Sequence Counter Use

    SCs. The following procedure is recommended: w Recommended procedure for sequence counter synchronization Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 27 Protocol version ....... Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 28 Table of contents Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 29: About Host Interface Modes And Features

    (1) Additional option. When using patient mode, the other 3 actions in the table are available. u Related topics • Patient mode (30) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 30: Patient Mode

    Do not use the same patient ID for more than one patient. In this section Patient entry (31) Patient modification (32) Patient deletion (32) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 31: Patient Entry

    Patient information is downloaded by means of BC40, Patient Entry. Example w Example of patient entry information u Related topics • Block 40: Patient Entry (74) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 32: Patient Modification

    Patient deletion is possible only if there are no orders attached to it. u Related topics • Block 41: Patient Deletion (74) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 33: Orders

    Those sets are programmed on the instrument and assigned to a number. A profile can contain individual tests or ratios. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 34 Line code 54: Order Information (97) u Configuring barcode setup (192) Example of order entry communication w Example of order entry communication Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 35 HbA1c, ordering one ratio will have the side effect of automatically ordering the second one. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 36 Otherwise each test and ratio will be ordered two times Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 37 About host interface features w Example of order entry with profile number Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 38 Orders Example of unspecific order request w Example of unspecific order request Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 39: Order Modification (Add Tests)

    • The order is finished and all results are accepted u Related topics • Block 11: Order Deletion (70) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 40: Host Query Mode

    Deletion block (Block 11) as soon as it has received all results belonging to a specific order. We recommend using the following procedure and timing when using host query: Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 41 (e.g. 60 seconds). Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 42 Host query mode Example of host query communication w Example of host query communication Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 43 About host interface features w Example of host query communication (continued) ...and so on. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 44: Result Requests

    Select Retransmit in the Process menu. We recommend using the following procedure and timing for the result request loop: Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 45 Related topics • Block 09: Result Request (68) • Block 10: Order Entry (69) • Block 11: Order Deletion (70) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 46: Example Of Result Query

    Result requests Example of result query w Example of result query communication Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 47 About host interface features w Example of result query communication (continued) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 48: Example Of Unspecific Result Request

    Result requests w Example of result query communication (continued) Example of unspecific result request w Example of unspecific result request Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 49: Example Of Result Request With Ratio (Collated Result Request)

    This is the reason why the two primary tests produce two calculated results. w Example of result request with ratio (collated result request) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 50: Protocol Version

    The Protocol Version request (BC92) is used to get the Version # of the HIF Protocol. u Related topics • Block 92: Protocol Version Request (79) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 51 Reference General codes......................53 Block codes ......................59 Line codes......................... 81 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 53 Instrument codes ......Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 54 Table of contents Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 55: Ascii Code

    US standard ANSI X3.4 for the interchange of information among communication devices. The first 32 values are reserved for control codes. w ASCII code Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 56: Control Characters

    End of text <EOT> End of transmission <LF> Line feed <CR> Carriage return <Space> Space <DC1> <DC3> XOFF y Control characters Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 57: Instrument Codes

    General codes Instrument codes The instrument code for the COBAS INTEGRA 400 plus analyzer is “14”. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 58 Instrument codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 59 Block 49: Patient Manipulation Response..Multi-configuration service blocks....Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 60 Block 99: Control Message ....Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 61: About Block Codes

    Notation of block codes (1) Number of iterations in all lines (2) Number of iterations in lines 02 and 12 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 62: Idle And Synchronization Blocks

    As an answer to a result request if no results are available Block 00 has no lines. Sync block configuration No block check. Idle block configuration Block check included. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 63: Result Blocks

    AGE rate line regardless of this parameter. If the AGE check was not required by the test, this line contains the values initialized by the instrument. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 64: Block 03: Control Result

    (2) n = 1 to 50. If result type selector 03 or 04 is used (results collated by order number) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 65: Block 05: Calibration Result With Lot Information

    AGE rate line regardless of this parameter. If the AGE check was not required by the test, this line contains the values initialized by the instrument. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 66: Block 06: Control Result With Lot Information

    = 1 (one test ID per result block) • n = 1 to 6 Results of different control orders are not collated. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 67: Block 07: Patient Results With Lot Information

    A possible error of a result request will be answered by block 08. Line Description code Error Message y Block 08 The message contains the associated error code. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 68: Block 09: Result Request

    Calibration and control results are only transmitted if enabled. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 69: Order Blocks

    (1) w = 1 if in patient mode (2) w = 0 if in patient mode (3) x = 1 to 200 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 70: Block 11: Order Deletion

    If several identical test orders exist, the first one that is found will be deleted. Ratio and profile test orders cannot be deleted via the host interface. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 71: Block 19: Order Manipulation Response

    Block 19: Response to an incorrect order entry with error in test order (1) x = 1 to 200 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 72: Response To An Order Or Test Deletion

    Description Iteration code Error Code 1 to x Test ID y Block 19: Response to an incorrect test deletion Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 73 Block 19: Response to an order/test deletion with default sample type if the order’s sample type was not default sample type x = 1 to 200 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 74: Patient Blocks

    Block 42 is used to change existing patient information Line Description code Patient ID Patient Information y Block 42 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 75: Block 49: Patient Manipulation Response

    Response to an incorrect patient entry, Line Description deletion, or modification code Error Message Patient ID y Block 49 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 76: Multi-Configuration Service Blocks

    Line Description code Slot State y Block 61 The rack numbers of the racks in the slots are sent. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 77: Block 62: Sample Tube Information

    If there is no sample tube information available, a block 69 with line 96 (service 61) is returned. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 78: Block 69: Service Request Response

    Status response to an MCS request is shown by block 69. Block 69 has one line. Line Description code Error Message y Block 69 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 79: Protocol Version Blocks

    Block 93 is the answer to block 92, protocol version request. Block 93 contains one line. Line Description code Protocol Version y Block 93 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 80: Control Messages Blocks

    Block 99 contains one line. Line Description code General Error Code y Block 99 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 81 Line code 96: Error Code ..... Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 82 Line code 99: General Error Code ... . . Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 83: About Line Codes

    Time format 2: hh:mm (hh in 24 h format) (used by COBAS Core/Core II). 5 character ASCII-string. Example: "22:07" y Formats of data fields used in line codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 84: List Of Line Codes

    Normal result without any flag: 00_•8.694475E+01_U/l•••_•• 0_••0_••0_••0_•0.000000E+00_•0.000000E+00<LF> ">TEST RNG" flag, HIF returns the value and the higher range limit: 00_10.694475E+01_U/l•••_•• 0_••0_•31_••0_•1.500000E+02_•10.00000E+00<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 85: Line Code 01: Result Time

    Line code 02: Control ID Description Format Range Line code QC-name y Line code 02: Control ID Example 02_ROC-N<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 86: Line Code 03: Standard Rates

    3 the K slope. • For all other electrodes, parameter 1 contains the associated slope value. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 87: Line Code 07: Abs Sample Check

    3rd value pair Absorbency value:6th wavelength, SR7.4 3rd value pair y Line code 07: ABS Sample Check Example 07_•0.0000_•0.0000<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 88: Line Code 10: Result Type Selection

    See Known host interface issues (178) u See Line code 53: Order ID (96) u See Configuring host communication (190) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 89: Line Code 11: Reagent Lot Information

    Example, N123A will be N123A • • • • • (•) represents a filler space Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 90: Line Code 13: Calibration Lot Information

    Example 15_22:07:59_23/04/2006<LF> Access date time is the point when the measurements are started on the instrument (scheduled date time) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 91: Line Code 16: Result Indexes

    A result will have a maximum of three indexes. If one index does not exist, it will be replaced with a right- justified zero. See the examples above. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 92: Line Code 40: Service Selection

    1 to 999 Rack number in slot 6 1 to 999 y Line code 41: Slot State Example 41_••3_350_••0_••0_••0_784<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 93: Line Code 42: Tube Information

    Test ID 1 to 999 Test state Test unavailable (blocked) Test available y Line code 43: Test State Example 43_•32_1<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 94: Line Code 44: Cal/Cs State

    Do not use the same Patient ID for more than one patient, otherwise results could be assigned to the wrong patient. u Related topics • Patient mode (30) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 95: Line Code 51: Patient Information

    Special order type Calibration order Calibration correction order Control order Attribute Immediate y Line code 52: Special Order Selection Example 52_03_T<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 96: Line Code 53: Order Id

    If the sample type is not transmitted, the default sample type (defined by test or rack definition) is used. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 97: Line Code 54: Order Information

    Depending on database set-up parameters Leadertext 1 and 2 Sample leadertext 1 Sample leadertext 2 y Line code 54: Order Information Example 54_••4_•4_S_These•are•21•chars•••<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 98: Line Code 55: Test Id

    Line code Priority modification type Change work list priority to STAT y Line code 57: Priority Modification Example 57_•2<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 99: Line Code 96: Error Code

    Description Format Range Line code Error code 01 to 08 y Line code 99: General Error Code Example 99_01<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 100 List of line codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 101 Messages Flags and error codes ..................103 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 103 List of line code 99 error codes ....114 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 104 Table of contents Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 105: About Flags

    Conditions under which result was generated Not yet used, currently set to ’0’ CALC Result error Evaluation of results Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 106: Flag X

    The control was not accepted. Not used y Sub Flag Q = (Flag X and 48)/16 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 107 Result was generated after dilution. Result was generated after concentration. y Sub Flag ^ = Flag X and 3 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 108: Flag Calc (Result Error)

    Upper test range exceeded (please refer to following note) TEST BLOCKED Used with collated results if a test is blocked (see note) y List of flag CALC Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 109 00 is either set to -9.999999E+99 or to 9.999999E+99. The range field is set to the appropriate value if applicable. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 110: Flag Qc

    > Critical Range Higher then critical Range DC > Delta Check in a value DC > Delta Check in percent y List of Flag QC Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 111: About Error Codes

    Cedex Bio HT Analyzer uses the following error codes: • Line code 96 error codes • Line code 99 error codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 112: List Of Line Code 96 Error Codes

    No test is loaded Service Action Status No Service Action definition is available y Line code 96 error codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 113 Sample type (undefined, *** or ??? are inappropriate) Any Order Manipulation Sample type (lab number) not found y Line code 96 error codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 114: List Of Line Code 99 Error Codes

    Line format error Erroneous line configuration, or possibly transmission error if block check off y Line code 99 error codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 115 Extended host interface of Cedex Bio HT Analyzer Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 117 Block 46: Test Status Response ....129 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 118 Block 96: Serial Number Request....138 Block 97: Serial Number Response ... . 138 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 119: About Block Codes For Extended Hif

    Notation of block codes (1) Number of iterations in all lines (2) Number of iterations in lines 02 and 12 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 120: Result Blocks

    (Line 06). There are 423 possible lines since each line is produced for every replicate (max. 3) and every cycle (max 141). Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 121: Block 03: Control Result

    = 1 to # of available tests (m is the number of tests with not yet transmitted QC results) • n = 1 (one control ID per result block) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 122: Block 04: Sample Results

    (5) y = 1 to z. The value of z is the total number of reruns executed for a single test result. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 123: Block 05: Calibration Result With Lot Information

    (Line 06). There are 423 possible lines since each line is produced for every replicate (max. 3) and every cycle (max 141). Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 124: Block 06: Control Result With Lot Information

    = 1 (one test ID per result block) • n = 1 to 6 Results of different control orders are not collated. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 125: Block 07: Sample Results With Lot Information

    (3) y = 1 to z. The value of z is the total number of reruns executed for a single test result. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 126: Operation Settings Blocks

    Line 96. The response message depends on the success of the request. Line code Description Error Message y Block 21 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 127: Service Action Blocks

    It is possible to retrieve all service action execution results after the specified date and time. Line code Description Date and time y Block 27 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 128: Block 28: Service Action Result Response

    Block 29 contains Line 96 and provides the eventual error encountered following request with Block 27. Line code Description Error Message y Block 29 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 129: Test Status Blocks

    Block 47 contains Line 96 and provides the eventual error encountered following request with Block 45. Line code Description Error Message y Block 47 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 130: Calibration Status Blocks

    Block 57 contains Line 96 and provides the eventual error encountered following request with Block 52. Line code Description Error Message y Block 57 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 131: Cassette Status Blocks

    Block 59 contains Line 96 and provides the eventual error encountered following request with Block 50. Line code Description Error Message y Block 59 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 132: Multi-Configuration Service Block

    1 to m Service Due Elapsed percentage y Block 64 (1) m is the total number of automatic service actions. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 133: Message Log Blocks

    Block 77 contains Line 96 and provides the eventual error encountered following request with Block 75. Line code Description Error Message y Block 77 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 134: Sample Order Status Blocks

    Otherwise if line 20 was used in block 80 only the requestd sample will be returned (m=1). Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 135: Block 85: Failed Order Status Request

    Block 85 contains Line 96 and provides the eventual error encountered following request with Block 80. Line code Description Error Message y Block 85 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 136: System Status Blocks

    Block 91 is the response to Block 90. It contains line 97. Line code Description System Status y Block 91 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 137: Date And Time Blocks

    Block 95 is the answer to Block 94, Date and time request. Block 95 contains one line. Line code Description Date and Time y Block 95 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 138: Serial Number Blocks

    Block 97 is the answer to Block 96, Serial Number request. Block 97 contains one line. Line code Description Serial Number y Block 97 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 139 Line Code 36: Cassette definition....158 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 140 Line Code 97: System status ....170 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 141: About Line Codes

    Time format 2: hh:mm (hh in 24 h format) (used by COBAS Core/Core II). 5 character ASCII-string. Example: "22:07" y Formats of data fields used in line codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 142: List Of Line Codes For Extended Hif

    12. Hence there can be up to 12 floating point numbers in the same Line. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 143: Line Code 08: Fp Raw Data

    Range description Line Code Validation Status Accepted Disabled Rerun Not handled y Line Code 14: Validation Status Example 14_1<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 144: Line Code 17: Test Execution

    Result differs from last result (up to n days before) by greater than defined value. %1% = [def. value] %2% = [unit] (F4) Result obtained using a dilution factor. (F1) y Flag codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 145 No end of sample segment detected. It takes too long for a sample segment to reach the electrode assembly. The tubing may be blocked or leaking. (F3) y Flag codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 146: Line Code 18: Cassette Information

    Example, 62159401 will be 62159401•• (•) represents a filler space Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 147: Line Code 19: Calibration Information

    Detailed information in the table below y Line Code 19: Calibration Information Example 19_11/04/2016_09:00:12_07-3718- 6•_176121••••_30/05/2016_62159401••_68354•••••_??? ???????_00/00/0000_??????????_00/00/0000_????????? ?_00/00/0000_R0••••••_0.0007479•_F•••••••••_5286.7 620•_??????????_??????????_??????????_??????????_? ?????????_??????????_••0<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 148 Nonlinear standard curve cannot be calculated due to calculation error. Action: Check calibration graph.Rerun calibration with fresh calibrators. (F3) y Flag codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 149 Result obtained after a repeated run. (F1) New calibration overwritten with old accepted calibration Any Calibration-Flag. y Flag codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 150: Line Code 20: Order Id

    Control Result Control Unit Control Flag Refer to following table y Line Code 21: Control Information Example 21_22/04/2016_08:31:37_07-7470- 7•_186387••••_31/05/2018_62159401••_68354•••••9.99 9999E+99_U/L•••_•17<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 151 The result exceeds than the upper measurable test range. (F3) The value exceeds the upper limit of a limit control. (F4) y Flag codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 152 Result (or a replicate) is erroneous or corrected. Result has not been accepted. Recommended action: Check results reaction curve to establish the cause of the deviation; repeat sample measurement. (F1) y Flag codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 153: Line Code 22: Order Id

    The messages are not cleared via host interface so, after a certain time, they should be deleted at the control unit. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 154: Line Code 25: Test Order Status

    No assigned values for control available Last control not accepted Repeat action not possible Test disabled y Blocking status flag codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 155: Line Code 26: Dilution Factor

    Line Code 26: Dilution Factor Example 26_••••2.1<LF> Samples on the instrument can only be diluted. The maximum dilution factor is 100. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 156: Line Code 27: Rerun Result

    If the calibration is required Calibration date When is the next calibration due. y Line Code 28: Test Status Example 28_17_•0_•••0_N_2_<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 157: Line Code 29: Cassette Status

    Calibration Pending Optional If the rack position is available Rack Position SlotID_RackNumber-RackPosition y Line Code 31: Calibrator status Example 31_07-6830-8••••••_CFAS••••_•6_•1_J•13-6••••<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 158: Line Code 32: Service Action Selection

    Lot number Cassette Lot number Cassette definition ID ID of the cassette type y Line Code 36: Cassette definition Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 159: Line Code 37: Tests Left

    Preparing Optional If the rack position is available Rack Position SlotID_RackNumber-RackPosition y Line Code 38: Diluent status Example 38_07-5635-0••••••_•1_O•140-8•••<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 160: Line Code 39: Cassette Status

    Yellow Requires mixing Yellow Reconstituting Yellow Preparing Yellow Empty Not on board Missing definition (unknown fluid) y Status codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 161: Line Code 40: Service Selection

    Electrode service Activate electrodes Prime ISE calibrators Clean ISE tower automatically Condition ISE tubing Initialize ISE module y IDs Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 162: Line Code 46: Currently Time Or Tests Elapsed

    Percentage of days occurred for service action to be performed y Line Code 48: Elapsed percentage Example 48_••••••••40_•••••••••32<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 163: Line Code 49: Rack Position

    Samples in the instrument can only be diluted. The maximum dilution factor is 100. If the dilution factor is omitted, the 1:1 factor will be used. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 164: Line Code 58: Service Action Result

    Replace Abs. halogen lamp Replace cleaner bottle Electrode service Deproteinize electrodes Etch electrodes Activate electrodes Replace reference (Ref) electrode y IDs Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 165: Line Code 60: Calibration Due

    If the calibration is required Calibration date When is the next calibration due. y Line Code 60: Calibration due Example 60_4_25/05/2016<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 166: Line Code 61: Test Status And Blocked Status

    Calculation not possible No ISE Electrode Activation not performed ISE module not ready Error in ISE module y Status codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 167: Line Code 62: Calibrator Id

    Range Line Code Message Icon Refer to following table for details y Line Code 82: Message Icon Example 82_•71<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 168 Temperature Okay Temperature Warning WasteDrain Error WasteDrain Okay WasteDrain Warning WaterSupply Error WaterSupply Okay WaterSupply Warning y Icon Codes Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 169: Line Code 83: Message String

    Format Range Line Code Serial Number SMP code and Serial Number y Line Code 94: Serial Number Example 94_CN123456<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 170: Line Code 97: System Status

    Cassettes Temperature in degrees temperature Cleaner Temperature in degrees temperature y Line Code 97: System status Example 97_•5_0_0_0_1_•853_0_•••37.1_•••12.6_•••24.2<LF> Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 171 Troubleshooting Troubleshooting ....................173 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 173 Collated results ......179 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 174 Table of contents Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 175: About Troubleshooting

    The Message Handler does not trace the host interface communication when used in the default configuration. Thus use the following procedure to enable host interface tracing. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 176: Enabling Host Interface Tracing

    5 To make these settings permanent, choose the Save button. I These settings only remain until the next shutdown. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 177: Viewing The Trace File

    The display now shows the all traced host interface communication. Using this view, you may scroll through the complete trace file. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 178: Known Host Interface Issues

    Related topics • Line code 53: Order ID (96) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 179: Collated Results

    10 03 rather than 10 04. u Related topics • Order entry (33) Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 180 Known host interface issues Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 181 Appendices Instrument setup....................183 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 183 Software-handshake ..... 197 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 184 Table of contents Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 185: Setting Up The Instrument For Host Communication

    Configure the racks for barcode reading. 6 Load your host application. • As a first check send an idle block. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 186: Preparing An Interface Cable

    9 Pin Conn 25 Pin Conn Signal Signal 25 Pin Conn. 9 Pin Conn SigGnd SigGnd y Pin assignments for RS-232 HW-handshaking Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 187: About The Connector Types

    Length The cable length should not exceed 15 m. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 188: Connecting The Interface Cable

    COBAS INTEGRA 400 plus analyzer and Cedex Bio HT Analyzer Host connector on COBAS INTEGRA 400 plus analyzer and Cedex Bio HT Analyzer. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 189 Data station rp5800 Host connector COBAS INTEGRA 400 plus analyzer and Cedex Bio HT Analyzer on the data station rp5800. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 190: Configuring Host Communication

    Handshake Hardware / Software Block Check True / False Line Terminator LF / CR+LF y Setup of interface parameters Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 191 If sample-type specific racks are not used, this Sample Type Short Name has to be included in the barcode. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 192: Configuring Barcode Setup

    The instrument recognizes the barcode type automatically. Configuration General > Barcode Use Barcode On Use Barcode On Enable the barcodes in the section. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 193 The barcode must not be shorter than the pattern you specified. Example of how to configure the barcode pattern and the alignment parameter Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 194 Setting up the instrument for host communication Configuration Lab > Racks Barcode reading can be independently enabled / disabled for every rack group. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 195: About The Rs-232 Serial Interface

    "0" / space / on • +3 V to +15 V • "1" / mark / off • -3 V to -15 V Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 196: Signal Description

    Ready for sending (clear to send) Data set ready 108/2 Data terminal ready Receive line signal detector y Signal assignment Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 197: About The Handshake

    As soon as the COBAS Instrument software is started, the host interface is ready to receive data. No initial SW handshake is required. Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 198 About the RS-232 serial interface Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 199 Index Index..........................201 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 201 Error codes, 103 Feedback, 5 Flags, 103 Host query, 40 Initilize, 26 Instrument codes, 57 Message structure, 18 Order entry, 33 Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...
  • Page 202 Index Roche Diagnostics COBAS INTEGRA 400 plus analyzer/Cedex Bio HT Analyzer · Software version 3.6/5.1 · Host Interface Manual · Version 1.24...

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