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Sciex 6500 series Manuals
Manuals and User Guides for Sciex 6500 series. We have
2
Sciex 6500 series manuals available for free PDF download: System User's Manual, Site Planning Manual
SCIEX 6500 series System User's Manual (181 pages)
Instruments
Brand:
SCIEX
| Category:
Laboratory Equipment
| Size: 2.62 MB
Table of Contents
Table of Contents
3
Chapter 1 Operational Precautions and Limitations
8
General Safety Information
8
Regulatory Compliance
8
Australia and New Zealand
8
Canada
9
Europe
9
United States
9
International
10
Electrical Precautions
10
AC Mains Supply
10
Protective Earth Conductor
11
Chemical Precautions
11
System Safe Fluids
12
Ventilation Precautions
13
Environmental Precautions
14
Electromagnetic Environment
15
Decommissioning and Disposal
15
Qualified Personnel
16
Equipment Use and Modification
16
Contact Us
17
Technical Support
17
Related Documentation
17
Chapter 2 Hazard Symbols
18
Occupational Health and Safety Symbols
18
Symbols, Indicators, and Labels: Packaging
20
Symbols, Indicators, and Labels: Mass Spectrometer
22
Documentation Symbols and Conventions
23
Chapter 3 Principles of Operation
24
System Overview
24
Hardware Overview
25
Theory of Operation-Hardware
28
Analyst Software Overview
30
Theory of Operation-Analyst Software
38
Chapter 4 Operating Instructions Sample Workflows
41
Chapter 5 Operating Instructions Hardware
44
Start up the System
44
Reset the Mass Spectrometer
46
Shut down the System
46
Plumb the Mass Spectrometer
47
Adjust the Integrated Syringe Pump Position
47
Plumb the Diverter Valve in Injector Mode
50
Plumb the Diverter Valve in Diverter Mode
52
Chapter 6 Operating Instructions Hardware Profiles and Projects
54
Hardware Profiles
54
Create a Hardware Profile
54
Add Devices to a Hardware Profile
58
Troubleshoot Hardware Profile Activation
59
Projects and Subprojects
60
Create Projects and Subprojects
60
Create Subprojects
61
Copy Subprojects
61
Switch between Projects and Subprojects
61
Installed Project Folders
62
Back up the API Instrument Folder
63
Recover the API Instrument Folder
63
Chapter 7 Operating Instructions Tune and Calibrate
64
Optimize the Mass Spectrometer
64
About the Verifying or Adjusting Performance Dialog
65
Results Summary
65
Chapter 8 Operating Instructions Automatic Optimization
67
About Automatic Optimization
67
Types of Sample Introduction
68
Automatically Optimize for an Analyte Using Infusion
68
Confirm the Presence of Compounds
68
Perform Automatic MS and MS/MS Optimization Using Infusion with a
71
Precursor Ion and an Unknown Product Ion
71
Check the Optimization Results
73
Automatically Optimize for an Analyte Using FIA
74
Chapter 9 Operating Instructions Acquisition Methods
81
Create an Acquisition Method Using the Acquisition Method Editor
81
Configure the Syringe Pump
82
Add an Experiment
82
Add a Period
82
Copy an Experiment into a Period
82
Copy an Experiment Within a Period
83
Scan Techniques
83
Quadrupole-Mode Scan Types
83
LIT-Mode Scan Types
84
About Spectral Data Acquisition
85
Chapter 10 Operating Instructions Batches
86
Set Queue Options
86
Add Sets and Samples to a Batch
87
Submit a Sample or Set of Samples
90
Change Sample Order
91
Acquire Data
91
Set Sample Locations in the Batch Editor
91
Select Vial Positions Using the Locations Tab (Optional)
92
Set Quantitation Details in the Batch Editor (Optional)
93
Stop Sample Acquisition
94
Import and Submit Batch Files
94
Build a Batch as a Text File
94
Import a Batch as a Text File
95
Batch Editor Right-Click Menu
95
Queue States and Device Status
96
Queue States
96
View Instrument and Device Status Icons
97
Queue Right-Click Menu
98
Chapter 11 Operating Instructions
100
Quantitative Analysis
100
Quantitation Methods
100
About Results Tables
101
Quantitation Methods and Results Tables
101
Create a Method Using the Quantitation Method Editor
101
Create a Results Table Using the Quantitation Wizard
103
Create a Standard Query
104
Results Table Right-Click Menu
106
Peak Review and Manual Integration of Peaks
107
Review Peaks
107
Manually Integrate Peaks
111
Peak Review Right-Click Menu
112
Calibration Curves
112
View Calibration Curves
113
Overlay Calibration Curves
114
Calibration Curve Right-Click Menu
114
Sample Statistics
115
View the Statistics for Standards and Qcs
115
Compare Results between Batches
116
Chapter 12 Operating Instructions Analyze and Process Data
117
Open Data Files
117
Navigate between Samples in a Data File
117
Show Experimental Conditions
118
Show Data in Tables
119
Show ADC Data
121
Show Basic Quantitative Data
121
Chromatograms
122
Show Tics from a Spectrum
123
Show a Spectrum from a TIC
123
About Generating Xics
123
Generate an XIC Using a Selected Range
124
Generate an XIC Using the Maximum Peak
124
Generate an XIC Using Base Peak Masses
124
Extract Ion by Selecting Masses
125
Generate Bpcs
126
Generate Xwcs
127
Generate DAD Data
127
Generate Twcs
128
Adjust the Threshold
128
Chromatogram Panes
129
Spectra Panes
130
Data Processing
130
Graphs
131
Manage Data
131
Zoom in on the Y-Axis
133
Zoom in on the X-Axis
133
Chapter 13 Reporter Software
134
Reporter User Interface
135
Generate Reports
137
Chapter 14 Service and Maintenance Information
138
Recommended Maintenance Schedule
138
Clean the Surfaces
140
Clean the Front-End
140
Symptoms of Contamination
140
Required Materials
141
Best Practices
142
Prepare the Mass Spectrometer
143
Clean the Curtain Plate
144
Clean the Front of the Orifice Plate
145
Put the Mass Spectrometer Back in Service
145
Empty the Source Exhaust Drain Bottle
145
Storage and Handling
148
Chapter 15 Mass Spectrometer Troubleshooting
149
Appendix A Operating Instructions Manual Optimization
150
About Manual Compound Optimization
151
About Scan Types
151
Manually Optimize an Analyte
151
Confirm the Presence of Compounds
152
Optimize MS-Specific Parameters
153
Determine the Product Ions for Optimization
155
Optimize Collision Cell Exit Potential for each Product Ion
156
Manually Optimize the Ion Source and Gas Parameters
157
Prepare the Ion Source
157
Optimize the Ion Source Parameters
157
Appendix B 6500 and 6500+ Series System Parameters
159
Appendix C Calibration Ions and Solutions
163
Appendix D Toolbar Icons
165
Revision History
173
Index
174
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Sciex 6500 series Site Planning Manual (39 pages)
Brand:
Sciex
| Category:
Laboratory Equipment
| Size: 0.64 MB
Table of Contents
Table of Contents
3
Chapter 1 Introduction
5
Customer Site Planner Responsibilities
5
FSE Responsibilities
6
During Installation
7
Customer Familiarization
7
Technical Support
8
Chapter 2 Site Planning Checklist
9
Customer Information
9
Requirements
9
Site Layout Requirements
9
Electrical Requirements
10
Gas Supply Requirements
12
Ventilation and Waste-Collection Requirements
13
Computer, Network, and Software Requirements
13
Environmental Requirements
14
Mass Spectrometer Bench Requirements
16
Solutions and Equipment Requirements
16
Product Familiarization
17
Additional Site Planning
18
Comments and Exceptions
18
Signoff
18
Appendix A Site Requirements
19
Site Layout Requirements
19
Laboratory Layout and Site Clearances
19
Weights and Dimension
20
Electrical Requirements
22
Mains Supply Connections
22
Mains Supply Fluctuations
25
Protective Earth Conductor
25
Uninterruptible Power Supply or Power Conditioner
25
System Electrical Specifications
26
Gas Supply Requirements
28
Optional Gas Generators
30
Ventilation and Waste Collection Requirements
31
Computer, Network, and Software Requirements
33
Acquisition Computer Requirements
33
Printer Requirements
33
LAN Connection (Optional)
33
Software Requirements
34
Environmental Requirements
34
Biosafety Requirements
35
Sound Pressure Level
35
Vibration
35
Solutions and Equipment Requirements
36
Customer Familiarization
36
Mass Spectrometer Operation
37
Appendix B Equipment Safety Categories
38
Revision History
39
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