Sartorius Stedim Biotech BIOSTAT B Manuals

Manuals and User Guides for Sartorius Stedim Biotech BIOSTAT B. We have 1 Sartorius Stedim Biotech BIOSTAT B manual available for free PDF download: Operating Manual

Sartorius Stedim Biotech BIOSTAT B Operating Manual (208 pages)

Brand: Sartorius Stedim Biotech | Category: Laboratory Equipment | Size: 7.63 MB

Table of Contents
3
About this Document
8
Validity
9
Accompanying Documents
9
Symbols Used
10
Safety Instructions
11
General Safety Instructions
11
Informal Safety Measures
12
Symbols Used on the Unit
12
Intended Use and Foreseeable Misuse
13
Residual Risks from Use of the Unit
14
Danger Due to Electrical Power
14
Danger Due to Components under Pressure
15
Hazards Arising from Bursting Culture Vessel
15
Danger Due to Gases
15
Danger Due to Oxygen
15
Danger Due to Nitrogen
16
Danger Due to Carbon Dioxide
16
Danger Due to Escaping Materials
16
Danger Due to Hot Surfaces
17
Danger Due to Rotating Parts
17
Danger Due to Use of Incorrect Consumables
17
Safety and Protective Systems
18
Main Switch
18
Safety Valves and Pressure Reducer
18
Overheating Protection
18
Personal Protective Equipment
19
Emergency Instructions
20
Operator Responsibilities
20
Personnel Requirements
21
Personnel Qualification Requirements
21
Personnel Responsibilities
22
Responsibilities
22
Unauthorized Personnel
22
Training and Instruction
23
Device Overview
24
Control/Supply Units
25
Biostat
25
B-MO Single / Twin
25
B-CC Single / Twin
25
Control Elements and Connections
27
Aeration Modules
31
Modules "Additive Flow 2-Gas
31
B-MO Single / Twin)
31
Modules "Additive Flow 4-Gas
32
B-CC Single / Twin)
32
Peristaltic Pumps
33
Culture Vessels
34
Univessel Glass
34
Univessel ® SU
35
RM Rocker 20 | 50
36
Stirrer Driver
37
Software
38
User Information
38
System Start
38
Principles of Operation
40
Device-Specific User Interfaces
40
User Interface
40
Header Line
40
Work Area
41
Footer
42
Display
44
Overview of the Main Function Keys
45
Overview of Selection Keys
46
Direct Function Keys for Selection of Submenus
46
Selection Lists and Tables
49
Password Protection of Individual Functions
50
Error Handling and Troubleshooting
50
Locking Functions
50
Transport
51
Inspection Upon Acceptance by the Recipient
51
Report and Document Transport Damage
51
Check Completeness of the Delivery
51
Packaging
51
Instructions for Transport Within the Company
52
Setup
53
Acclimatization
53
Ambient Conditions
53
Work Surfaces and Loads
54
Laboratory Energy Sources
57
Electricity
57
Manufacturer's ID Label
58
Tempering Medium
59
Gas Supply
60
Startup
62
Installation Material
62
Connecting the Device to the Power Supply
63
Connecting Laboratory Water Supply to the Device
64
Connecting Laboratory Gas Supply to the Device
65
Connecting the Stirrer Driver (Only Univessel Glass / Univessel SU)
66
Connecting the Univessel
67
SU Holder
67
Connecting the Barcode Scanner
67
Connect RM Rocker 20 | 50 for Cultibag RM
68
Connecting the Sensor Cable
68
Connecting the Tubes for Aeration
68
Connecting the Temperature Control
69
Jacketed Culture Vessels / Single-Walled Culture Vessels with Heating | Cooling Jacket (Only Univessel Glass / Univessel SU)
69
Cultibag RM Temperature Control
71
Heating Jacket
72
Glass / Univessel ® SU)
72
Connecting the Exhaust Cooling Hoses (Only Univessel Glass)
73
Turning the Device on and off
74
Preparing and Running the Process
75
Overview
75
Preparing the Glass Culture Vessels
75
Connecting Transfer Lines
76
Filling the Culture Vessel with Culture Medium
78
Univessel ® Glass / Univessel ® SU
78
Cultibag RM
78
Sterilizing Glass Culture Vessels
78
Preparing the Cultivation Process
79
Mounting the Agitator Drive
80
Heating | Cooling Jacket Installation
82
Installing the Heating Blanket
83
Connecting the Aeration Modules
85
Conducting Preliminary Steps
85
Univessel ® SU Safety Valve Station
85
Connecting the "Additive Flow 2-Gas" Aeration System
86
Connecting the "Additive Flow 4-Gas" Aeration System
87
Preparing the Corrective Solution Supply
88
Performing a Process
90
Setting up the Measurement and Control System
91
Guaranteeing Sterility
92
Carrying out the Cultivation Process
92
Main" Menu
93
General Information
93
Process Displays in the "Main" Menu
94
Direct Access to Submenus
94
Trend" Menu
96
Trend" Display
96
Configuring the "Trend" Display
97
Setting the Trend Display for Parameters
97
Setting the Parameter Display Range
97
Resetting the Display Range
98
Setting the Trend Display Color
98
Defining a New Time Range as "Time Range
98
Calibration" Menu
99
General Information
99
Ph Calibration (Conventional Sensor)
99
General Information on the Ph Sensor
99
Calibration Ph-#" Submenu
100
Perform Calibration
101
Direct Input of the Zero Offset and Slope
102
Perform Recalibration
102
DO Calibration (Conventional Sensor)
103
General Information on the Po 2 Sensors
103
Submenu "Calibration Po
103
Perform Calibration
104
Direct Input of the Zero Offset and Slope
105
Optical Ph and Po Sensors
105
Signal Quality of the Optical Probes
106
Notes on Calibration
107
Ph Calibration (Optical Sensor)
107
Calibration Ph-#" Submenu
108
Enter Initial Calibration Data
109
Performing Recalibration
110
Configuring the Measurement Cycle for Ph Measurement
111
DO Calibration (Optical Sensor)
111
Submenu "Calibration Po2
112
Perform Initial Calibration
113
Performing Recalibration
114
Configuring Measurement Cycles for DO Measurement
114
Totalizer for Pumps and Valves
115
Scale Taring
117
Controller" Menu
119
Functional Principle and Equipment
119
Controller Selection
120
General Controller Operation
121
Setpoint Profile
122
General Controller Parameterization
123
Output Limits
124
Dead Zone
124
Controller Parameterization Menu Screen
124
PID Parameters
125
PID Controller Optimization
125
Guide and Slave Controller (TEMP, JTEMP) Temperature Measurement
125
Temperature Measurement Without Slave Controller (TEMP)
127
Speed Regulation (STIRR)
128
Antifoam Controller "FOAM
129
Level Control with Level Sensor (LEVEL)
130
Gravimetric Level Control (VWEIGHT)
131
Gravimetric Filling Pump Controller "FLOW
132
Filling Pump Controller (SUBS)
133
Gas Controller (Gas Filling Controller / Gas Flow Controller)
134
Ph Controller
135
Function
135
Controller Operator Screen
135
Parameter Settings
136
Acid, Base, and CO Supply-Driven Ph Control
136
DO Control Methods
137
Po Controller CASCADE (Cascade Controller)
138
Po Controller ADVANCED (Polygon Controller)
141
Aeration Strategies
147
RM Rocker 20 | 50 Controller Functions
150
Introduction
150
Angle Control
151
Position Settings "POSITIONING
152
Aeration Rate
154
Additional Information
155
Settings" Menu
156
General Information
156
Settings
158
Measuring Range Settings
158
Manual Operation
160
Manual Operation for Digital Inputs
161
Manual Operation for Analog Inputs
165
Manual Operation of Analog Outputs
166
Manual Operation for Controllers ("Control Loops")
168
Manual Operation of Sequence Control ("Phases")
169
Externally Connected Devices
170
Service and Diagnosis
171
Faults
172
Safety Instructions
172
Troubleshooting
172
Hardware-Related Faults
173
Fault Table "Contamination
173
Troubleshooting Table "Counter Cooling System
174
Troubleshooting Table "Aeration and Ventilation
174
Process-Related Faults / Alarms
175
Alarm Triggering
175
Alarm Overview" Menu
176
Process Value Alarms
176
Alarms for Digital Inputs
179
Alarms, Meaning and Corrective Measures
180
Process Alarms
180
System Alarms
181
Cleaning and Maintenance
182
Cleaning
183
Cleaning the Device
183
Cleaning the Culture Vessels
184
Cleaning and Maintaining Heating Jackets
184
Maintenance
186
Carry out Maintenance Work on Function Elements
186
Safety Component Maintenance
186
Maintenance Intervals
187
Storage
189
Disposal
190
General Notes
190
Hazardous Materials
190
Decontamination Declaration
191
Decommissioning the Unit
191
Disposing of the Unit
192
Specifications
193
Ambient Conditions
195
Water Hardness Conversion Table
195
Conformity & Licenses
196
EC Declaration of Conformity
196
GNU Licensing
196
Appendix
198
Service Center
198
Decontamination Declaration
198
Setup Drawings
200

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Sartorius Stedim Biotech BIOSTAT B Operating Manual (208 pages)

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